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Sarms – Selective modulators of androgen receptors, which were designed to replace a variety of anabolic steroids with their rich bouquet of various side effects for the body. These drugs can safely be called a new solution for those who do not want t...
Sarms – Selective modulators of androgen receptors, which were designed to replace a variety of anabolic steroids with their rich bouquet of various side effects for the body. These drugs can safely be called a new solution for those who do not want to resort to "strong chemistry", and wants to simply increase quality meat and become more powerful without any side effects. The main advantage is that during their development all the achievements and advantages of predecessors were used. But there is more. Earlier we have said that modern medicine makes a strong emphasis on safety. And this vector completely passed through SARMs, because at the creation of these drugs researchers focused on reducing the adverse effects of the main male hormone-testosterone on the prostate.
The principle of their functioning is very simple - SARMs join the receptors of male sex hormones and interact with them directly. In fact, the positive effects of these additives on the growth of muscle mass and strength indicators became known at all recently. However, the fame of efficiency and, most importantly, the safety of these pharmacological means with the speed of sound flew through the bodybuilder series, which served as a stimulus to the active use of SARMs in the big sport.
Note that nowadays many pharmaceutical companies already have on hand some types of these drugs that have successfully overcome a number of different clinical studies in humans. What exactly-we will consider next.
The word MSAR (SARM) stands for "Selective androgen receptor modulator", like other selective receptor modulators, SARMs can either block or stimulate, hormone receptors in the nucleus of the cell depending on Focus of their actions. Consequently, they can block or stimulate receptors in the body tissues selectively, simulating a beneficial effect in one tissue, and at the same time minimizing the unwanted effects of synthetic steroid hormones in other tissues. SARMs belong to the class of androgens (a specific class of hormones, which are produced by sexual glands, one of these hormones-is known to all testosterone). SARMs can be attached to the androgen receptors in the cell, resulting in a complex process of activating certain genes responsible for muscle hypertrophy, regeneration of bone and connective tissues.
In fact, anabolic androgenic steroids (AAS) and prohormones are also associated with androgen receptors, resulting in muscle growth. However, SARMs show their anabolic activity only in muscle and bone tissue, and have minimal impact on other tissues and in the body, such as on prostate, as opposed to AAs, which can be very harmful to this gland. As an added benefit, SARMs is used orally rather than injected, unlike most of the AAS.
Despite the fact that SARMs are produced in oral form, they are not toxic to the liver.
Due to the fact that SARMs are very selective on action on androgen receptors only in certain tissues of the body, they can be very useful for building excellent muscle mass without side effects. Also SARMs are not converted into estrogens, unlike AAs, which, of course, is their distinctive feature and a huge advantage.
Steroids are usually prescribed by doctors in two cases. The first is to treat muscular atrophy caused by serious diseases such as cancer or osteoporosis. The second case is the appointment of steroids as hormone therapy (HRT). However, the main problem of steroids is that they almost always cause a lot of side, undesirable effects.
Scientists decided to develop drugs that would have all the advantages of AAS, but at the same time the disadvantages of AAS would be reduced to almost zero. Thus the light appeared sarmy (Sarms), which are attached to the receptors selective, selectively stimulate only the growth of muscles, thereby avoiding unwanted side effects.
Subcategories
GW501516 or Cardarine acts as a pparδ-modulator (Activator of proliferation of Delta receptors). GW501516 Activates and stimulates the absorption of glucose in the tissues of skeletal muscles. In other words, GW501516 changes the energy preferences of the body from carbohydrates to fats.
The connection Cardarine was opened relatively recently, but the effect that produces the drug is very interesting. It has been proven by experience that GW501516 really makes it possible to improve athletic performance by strengthening the ability of muscles to work without fatigue. It is especially effective in training loads, and the closer the athlete approaches to the limit of his abilities, the better GW501516 works, warning the feeling of fatigue.
The work mechanism of GW501516 is associated with the impact on the process of energy production in the body. Thus, the substance increases the formation and then the oxidation of fats, which serve as an important source of energy during training. Also thanks to GW 1516 increases the speed of blood flow, resulting in a stable transport of lipids to the places of their splitting. In addition GW501516 affects the processes of carbohydrate metabolism.
Also GW501516 supports cardiovascular system: When using anabolic steroids, some of which increase the pressure, Cardarine allows to normalize its level.
Significant increase in endurance & very fast Recovery.
- No side effects with proper application;
- is not a catabolic;
- allows to burn fat and keep muscles;
- increases good and lowers bad cholesterol.
Research: Cardarine demonstrated stimulation of oxidation of fatty acids in men who are prone to fullness. GW501516 was proposed as a potential drug for the treatment of obesity.
GW501516 increases the intake of glucose in skeletal muscle tissues and increases the expression of muscle genes involved mainly in the utilization of lipids. This changes the metabolism in the body in order to use burnt fat to produce energy instead of carbohydrates or muscle protein. This allows obese patients to lose fat effectively without experiencing muscular catabolism or hunger problems that are associated with low blood sugar levels.
In rats treated GW501516, there was an increased metabolism of fatty acids in skeletal muscles and protection from the induced diet of obesity and diabetes of the second type. At macaques-rhesus with obesity, GW501516 increased the amount of lipoprotein high density (HDL) and reduced the level of lipoprotein very low density (VLDL). The mechanism of action by means of which agonists pparδ increase the number of lipoprotein of high density, is the result of reinforced expression of the ABCA1 cholesterol transporter.
Recommended Dosage - 20 mg per day.
Active Substance: {4-[({4-methyl-2-[4-(trifluoromethyl) phenyl]-1.3-thiazol-5-yl} methyl) sulfanyl] -2-methylphenoxy} acetic acid How to: Take 1 capsule once a day at meal time.
Igandrol/Ligandrol/LGD-4033 is a safe and effective tool for pharmacological support of power training from the group of selective androgen receptor modulators (SARMS). Not being a peptide or steroid hormone, ligandrol enhances the anabolic response to training stimuli, accelerates recovery, boosts fat burning and promotes muscle relief.
Ligandrol is actively applied bodybuilders in the Massonabora period. The anabolic effect is achieved even in the minimum dosage: only 1 mg/day increases muscle growth. Use the drug for drying, slimming and drawing muscle relief, and thanks to the ability to improve speed and strength, it is popular in weightlifting, powerlifting and martial arts.
Ligandrol can be used by both men and women. Duration of action-24-36 hours, enough 1 capsule per day.
Ligandrol is a selective androgen-type receptor modulator. The term "selective" means that it selectively activates the testosterone receptors in muscle and bone tissue, but does not affect the receptors in the pituitary gland, sebaceous and genital glands, prostate and hair follicles. This feature allows you to achieve the desired athletic result without the negative effects inherent in anabolic steroids.
By activating the testosterone receptors in the muscles ligandrol enhances the synthesis of muscle protein, accelerates the replenishment of muscle glycogen, increases the efficiency of oxidative reactions and spurs the utilization of fats. Stimulation of androgenic receptors in the bones prevents resorption of calcium and increases the strength of bone tissue. The similar effect (increase of a resource of durability) is observed in joints, tendons and ligaments, thanks to what Ligandrol recommend to use for prevention of traumas.
Drops in the level of testosterone, LH or FSH on the course of Ligandrola will not be, because the receptors that affect the synthesis of hormones, the drug does not activate. does not act on it and enzyme aromatase, which eliminates the risk of increasing estrogen levels and the development of gynecomastia. In addition, the Ligandrola course does not delay fluid-a set of mass quality, without further rollback.
Ligandrol is considered to be the most effective sarms in terms of muscle mass. The powerful anabolic response makes it possible to use it in Massonabore as solo courses and in combination with other selective androgen modulators. It is possible to combine ligandrol with steroids and peptides, but in this case Poslekursovaja therapy becomes obligatory.
When preparing for the competition, the ability of ligandrola to boost fat burning and change the composition of the tissues goes to the fore. This feature is used bodybuilders, fitness models and Bikinistki. It is impossible to show relief without Farmpodderzhki. AAS courses are fraught with side effects, while sarms help to gain competitive shape without negative consequences.
Among no less desirable effects-the growth of power indicators, increased physical endurance, acceleration recovery. Ligandrol makes training more intense and productive. The working weights go up, the number of sets and reps grows. It is possible to use more intensive training methods. Muscles recover faster, and strengthening ligaments and joints helps to avoid injuries and injuries.
Issued in capsules;
Does not affect the secretion of testosterone, FSH and LH;
Stimulates a set of muscle mass;
improves composition of tissues;
accelerates fat burning;
Effective in the course of solo and well combined with other sarms;
Strengthens joints and ligaments.
Recommended dose: During the recruitment of muscle mass 1-2 capsules per day, the duration of the course-8 weeks. Athletes who have moved into the drying phase should reduce the dosage to 1 capsule per day every day. The duration of the course remains the same.
Ibutamoren/Ibutamoren/MK-677 is an innovative tool for pharmacological support of the training process. The tool is safe and efficient! Acting on specific receptors in the pituitary gland and hypothalamus, ibutamoren enhances the synthesis of endogenous growth hormone, boost muscle hypertrophy and stimulates fat burning.
In fitness and bodybuilding ibutamoren used to stimulate anabolism and improve the composition of tissues. Effective in the period of massbuilding, during drawing of relief, in preparation for competitions. Improves energy exchange. Increases stamina and peak strength. Models carbohydrate and lipid metabolism, translates muscles to fuel from fatty acids, helps to get rid of excess fat even on the background of errors in the diet.
The listed effects are achieved without negative impact on the hormonal balance. Ibutamoren does not apply to peptides or steroid hormones. The course does not suppress the production of testosterone and does not increase the level of estradiol and prolactin, which is peculiar to steroids. This feature eliminates the need for a PBC and eliminates the phenomenon of rollback-the loss of muscle mass, inevitable after the steroid courses.
The mechanism of action Ibutamoren seems confusing, but in fact everything is simple. The drug activates the specific receptors of the pituitary gland and hypothalamus. Ghrelin receptors are the target for endogenous hormone ghrelin, which emit cells of the digestive system. Interacting with receptors, ghrelin regulates appetite, and at the same increases secretion of growth hormone.
Similarly acts Ibutamoren, and therefore in the scientific language it is called agonist Ghrelin receptors. (agonist = activator). Communicating with the receptor, Ibutamoren mimics the action of Ghrelin and "tells" the pituitary gland that it is time to synthesize growth hormone (somatotropin). The increase in secretion of growth hormone triggers a cascade of metabolic shifts to which all athletes aspire, from professional bodybuilders to guys, weightlifters and fitness enthusiasts.
Important! The effect of the drug ibutamoren long. Duration of stimulation of secretion of growth hormone up to 8 hours!
The increase in the peak and basal secretion of the growth hormone translates the body into a anabolic state. On the background of the reception Ibutamoren amplified protein synthesis, in particular, contractile proteins muscle tissue. Accelerates recovery after exhausting power and cardio sessions. Energy reserves increase, endurance is growing, and with it intensity and productivity of trainings.
In muscle tissue growth hormone induces production IGF-1 (insulin growth factor), which boost proliferation and differentiation cell-satellites-predecessors of muscle fibers. The appearance of new muscle cells leads to a qualitative set of mass due to hyperplasia. Simply put, muscles grow not due to fluid retention (this is typical of steroid courses), but due to the increase in the number of contractile myofibrils.
Boosting secretion of GR and IGF-1, Ibutamoren affects energy metabolism. The muscles increase the number of mitochondria, accelerates the oxidation of fats and the utilization of fat reserves. The role of carbohydrates in the energy supply of muscle contraction decreases slightly, which causes the muscles to use fats more actively. This nuance guarantees the improvement of the composition of the tissues even on the background of minor errors in the diet.
Another reason to buy a ibutamoren is its ability to reduce the possibility of injury. Ibutamoren increases the mineral density of the bone, strengthens ligaments, tendons and joints. In power sports prevention is valued on the weight of gold, because the damage for a long time knocked out of the training schedule and extremely negatively affect sports performance. Preventive action is explained by the same increase in secretion of GR and IGF-1.
Safe: does not inhibit the synthesis of testosterone. Does not increase the level of estrogen.
No side effects: no gynecomastia, no acne, no hair loss.
Convenient: Form of release-capsules. No need for injections.
Set of mass quality: muscles do not fill with water. There is no rollback phenomenon.
Suppresses catabolism: Blocks protein decay.
Anabolic effect: stimulates the synthesis of contractile proteins.
Additional Benefits:
Boost Fat burning;
improves composition of tissues;
Raises efficiency of energy exchange;
Increases endurance and physical performance;
Hypertrophy of the muscles is due to hyperplasia!
Recommended Dose: 1-2 capsules, 1-2 times a day.
Ostarine - a new type of steroid for a quality set of muscle mass. Provides dry mass without excess fat. It is absolutely legal and has no side effects. Already now you can buy Ostarine.
Ostarine is the most popular sarms. Widespread throughout the world. It is used for a set of high-quality dry muscle mass. Also known as the GTX-1024 and MK-2866. After the application of Ostarine is not required PBC. What are the advantages of Ostarine. This is:
4 to 6 kg muscle gain for a 2-month course.
The ratio of anabolic to androgenic activity is 10 to 1 (according to studies in testosterone the same rate is 1 to 1).
Ostarine (MK-2866) – only affects your bone and muscle tissues. Due to this the general hormonal background remains unchanged.
No pct after course.
Absolutely legal.
Application:
Take 1 capsule Ostarina an hour after breakfast.
Ostarol selective androgen receptor modulator
-5-7 kg increase for two month course
-The best drug on the PCT
-The best preparation for the bridge
-Reduction of subcutaneous fat
-long period of 24h
-1 reception per day
-Restores bone tissue
-does not require PCT (use of rehabilitation drugs)
-Do not aromatize
-Does not affect the arc
-Non-toxic
-Missing "phenomenon rollback"
-Legal
-Powerful anabolic connection
-Can be used by men and women
-Increases strength and endurance
-Promotes rapid recovery
Daily use of the drug provides the growth of dry quality muscle mass, a significant increase in strength and endurance athlete. An important feature of Ostarine is its direct impact on muscle tissues without affecting the receptors of other organs in the human body. Noticeable increase in results is achieved without additional restrictions in the diet. The drug does not delay water and does not provoke side effects, typical of the therapy of steroid substances.
Ostarine provides an average increase of 2-5 kg of dry muscle mass for a month of use with an active training program in the gym. Reception of the drug promotes muscle growth, restoration of cartilage and bone tissues.
Athletes have noticed that the reception of Ostarine does not require any additional use of means for recovery. Sportsmen, who use Ostarine note that in most cases it is not felt "roll back", when after the cessation of the application of the lowering of sports indicators and there is a loss of muscle mass. In addition, the Ostarine index of anabolic/androgenic activity is 10 times higher than that of testosterone.
Being a sufficiently potent drug, Ostarine is not toxic to the body and is equally effective for both men and women. has no negative impact on libido. The drug is absolutely legal and is not considered doping.
Stimulates a set of muscle mass;
Strengthens and restores bones and joints;
Increases endurance;
Improves mood.
Ostarine is secure:
No influence on the "pituitary-hypothalamus-testicles" arc;
No prostate growth;
No "aromatization";
No need for hormone recovery;
Absolutely legal.
Radium/Radium/RAD-140-a new word in sports pharmacology. A non-steroidal muscle growth generator with high anabolic potential, provides a quick set of mass without side effects. At the same time, it boosts fat burning, increases endurance, increases speed and strength, strengthens ligaments, joints and bone tissue.
Anabolic state of the body-the dream of any athlete, but many are frightened by the side effects of steroid courses. Radium solves this problem. The innovative drug belongs to a group of SARM, selective androgen receptor modulators, and the key word here is selectivity.
RAD-140 selectively activates androgen receptors in muscles and connective tissues (fat, bone, cartilage). On the androgen receptors in the genital glands and in the endocrine organs SARM RAD-140 acts differently-partially blocks, which eliminates the risk of negative effects of the anabolic course. In this specificity lies the secret of high efficiency combined with an excellent security profile.
Is anabolic response possible without side effects? 20 years ago There was no affirmative answer to this question, but the situation changed cardinally. A short excursion to biochemistry will help you understand how the impossible became a reality.
The negative effects of testosterone and synthetic analogues are associated with two enzymes of our body-aromatase and 5-alpha-reductase. Aromatase converts testosterone into estrogens that cause gynecomastia and water retention. 5-alpha-reductase converts testosterone into dihydrotestosterone, and that leads to hair loss, acne and oppression of the synthesis of sex hormones.
Radium and other selective androgenic modulators (such as: Ostarin, Kardarin, Ligandrol, Andarin, Ibutamoren) have a unique chemical structure. The molecule has no steroid structure, is not subjected to aromatization and is not converted into estrogens. Not valid on it and 5-alpha-reductase. Hence there is no risk of gynecomastia, no oppression of the production of sex hormones, no need for a PBC. There is no phenomenon of rollback-the muscle mass accumulated on the course will remain with you!
But the androgen receptors in the muscles radium activates 100 times stronger than testosterone. Hence the forced synthesis of muscle protein and a quick set of dry mass. Stimulation of androgenic receptors of adipose tissue simplifies weight loss and increases efficiency of training on relief. Also RAD-140 accelerates recovery after training, has anti-catabol action and protects the muscles in the drying phase.
So, the target of the radium-cell connective tissue, which includes muscle tissue, bone and fat. On the pituitary gland, hypothalamus, prostate and genitals the drug is not affected. Selective androgenic modulators do not depress hormonal regulation centers in the brain and do not suppress the secretion of their own testosterone.
Thanks to its unique biochemical properties, selective androgen receptor modulators have become incredibly popular. Stars of professional bodybuilding actively use in the Protocols safe SARM. Their example is followed by athletes amateurs, novice athletes and adepts of a healthy lifestyle, interested in a set of dry muscle mass.
Reception SARM not contradict the principles of HLS. Radium is not toxic to the liver, does not increase the level of cholesterol, does not oppress the sexual arc. It is recommended to newcomers of the iron world and guys who want to get away from the "steroid needle" and are looking for a way to help the body in the period of abolition of hormonal support.
Radium/Radium (RAD-140/happy-140)-a safe way to sports success. It is effective in mass building, slimming and drying. Gives an increase in quality mass, endurance and peak strength. Improves the composition of the tissues. If you are tired of craving iron without visible effect, buy RAD-140 immediately it in the recommended dose, and the result will not wait!
Briefly about the benefits of the drug radium:
Convenient: Forget about the injections! The product is happy to be released in capsules.
Safe: does not inhibit the synthesis of testosterone, does not lead to gynecomastia.
Effective: the guarantee of the growth of dry mass, speed-strength and burning podkodnogo fat.
How to take RAD-140?
Recommended dose: During the recruitment of muscle mass 1-2 capsules per day, the duration of the course-8 weeks.
Andarine/Andarin/S-40503 is a selective androgen-type receptor modulator developed for the treatment of osteoporosis and muscular atrophy. In bodybuilding, fitness and power Sports is applied due to the excellent safety profile in combination with anabolic and lipolytic activity. Does not apply to peptides or steroids. does not inhibit the synthesis of endogenous testosterone, has no negative impact on the prostate, liver, cardiovascular system.
Bodybuilders include Andarine in pharmacological support protocols to strengthen muscle density and draw relief. Bikini and Fitness models use Andarine to reduce the percentage of adipose tissue, powerlifters-to force the power indicators. It is also popular among the representatives of sports disciplines requiring physical endurance (athletics, cycling).
Also Andarine recommend boxers, wrestlers, representatives of mixed martial arts. In combination with the right diet, it gives a net increase in speed and strength, and athletes progress without risk of getting out of the native weight category.
Andarine refers to sarms (selective modulators of androgen-type receptors). The characteristic feature of an innovative group of pharmacological means is selective anabolic and androgenic activity in muscles, adipose tissue and bones. Sarms do not act on the pituitary gland, prostate, genital glands and hair follicles, which eliminates the risk of developing complications inherent in anabolic steroids.
Activating androgen receptors in the muscles, andarine induces protein synthesis, accelerates the compensation of glycogen, slows down and stops catabolic processes. Increases the utilization of fatty acids in oxidative reactions. Increases the mineralization of bone tissue, increases the resource strength of ligaments, joints, tendons.
Athletes who are familiar with the intricacies of strength training, compare Andarine with Winstrol (stanozolol), but without side effects. Taking Andarine leads to an increase in the density of muscle tissue. The set of mass is very high quality, without rollback at the end of the course. Muscles literally become stone, and thanks to burning of subcutaneous fat the clear relief is drawn.
Taking into account specificity, Bodibilderam, Fitnesmenam and Bikinistkam Andarine recommend to apply in preparation for competitions and during drying periods. Intensive oxidation of fats in combination with redistribution of calories simplifies the achievement of the goal. Athletes practicing steroid courses andarine should be connected in the second half of the cycle and in the PBC phase.
Great results will be given to sports enthusiasts and people who want to lose weight without the side effects of hormonal drugs. In the course of admission andarine calories of food go to the recovery and growth of muscles, not deposited in adipose tissue, which, combined with the intensification of lipid metabolism makes slimming inevitable even with small errors in the diet.
Another area of application Andarine-prevention and treatment of gynecomastia, baldness and other side effects of steroid courses. Andarine prevents the binding of DHT (dihydrotestosterone) with receptors and prevents hair loss. Hinders the development of gynecomastia, reduces its development, if the troubles could not be avoided.
In power sports and martial arts Andarine used to build up peak power and speed. In athletics and cycling-to improve physical endurance. Representatives of all sports disciplines take sarms to strengthen the musculoskeletal system and prevent injuries.
Gives a quality set of mass without rollback;
Increases the density of muscle tissue and shows relief;
Simplifies the process of slimming and drying;
Increases endurance and strength;
Increases the strength of bones, ligaments and tendons;
Prevents and minimizes the side effects of steroid courses.
Recommended Dose: 1-2 capsules per day. Take Andarine recommend by cyclic scheme-2 capsules a day for 5 days, then 2 days break. The daily dose should be divided into 2 admission. For prevention and treatment gynecomastia Andarine take 1 capsule for 6 days, then 1 day break.
S9009 is a powerful and safe catalyst for metabolic processes. It is used for weight loss, drying, in the course of relief. Not being a hormone or a hormone, S9009 accelerates metabolism, slows the synthesis of triglycerides, increases the oxidation of fats and glucose in skeletal musculature. S9009 increases endurance and increases the effectiveness of training without the side effects characteristic of hormonal drugs.
It is necessary to start with the fact that in adipose tissue, liver and skeletal musculature there is a special signal protein which is called Rev-Erb. This protein plays the role of regulator, which accelerates the metabolism. The "active" Rev-Erb amplifies the decay of fats and slows down their synthesis, increases the rate of oxidation of glucose, in the muscles formed new mitochondria.
S9009 - A unique substance that can bind to the protein Rev-ERB and translate it into an active state. The stimulation of Rev-ERB is accompanied by changes at the molecular and biochemical level, among which the most important and interesting in terms of fitness are:
Increase in the number of mitochondria in the muscles;
Acceleration of metabolism;
Deceleration of the synthesis of triglycerides and cholesterol;
Acceleration of oxidation of glucose and fats in muscles.
What does it mean in practice? On the background of the reception S9009 faster destruction and oxidation of fats. The muscles get more energy, hence the increase in endurance. Aerobic and force loads are easier to tolerate. Training becomes more effective. The volume of work carried out in training is increased: you raise more tonnage, do more approaches, complete more repetitions, run farther and faster.
In experiments on laboratory animals The fantastic results were received: for a unit of time the experimental beasts ran a distance which on 50% exceeded usual. Simultaneously increased and time under load-the same 50%! This is due to the fact that the additional mitochondria generated energy that allowed to cope with a large amount of work.
On the course S9009 the level of metabolism at rest is increased by 5%, it is also proved by experimental way. Instead of fat reservation "for later", the body burns it to cover the energy needs of the main exchange. By adding a more efficient metabolism of carbohydrates (active oxidation of glucose in skeletal muscles), we get the energy consumption at rest, which is comparable to the energy costs of standard cardio training.
In the liver is slowed synthesis of lipids, bile acids and cholesterol, and this is another bonus to the program of intensive burn. Adipocytes slows down the formation of triglycerides-the main molecules of fat storage, and it prevents the accumulation of surplus even in small errors in the diet.
Changes in the biochemical analysis of blood are also impressive. Taking the drug S9009 leads to lower concentration in the blood plasma:
Insulin by 35%;
Glucose by 19%;
Free fatty acids by 23%;
Total cholesterol by 47%;
Triglycerides by 12%.
It should be said that such changes in the hand are not only athletes. With increased blood content of the above indicators, the risk of developing metabolic syndrome, obesity, atherosclerosis, arterial hypertension and heart disease increases. It turns out that S9009 not only promotes growth of sports achievements, but also strengthens health, reducing the above indices, protects heart and vessels.
There is one more "trifle" left. S9009 reduces the concentration of cytokines in the blood plasma, responsible for the development of inflammatory processes. The level of interleukin-6 decreases by 72%, and this is a colossal help in combating inflammation, muscular pain and painful sensations in the joint area!
Obviously, the main area of application of sr9009 in sports is the fight against fat deposits. It is not only about excess fat in people who make the first steps in fitness. Of course, Stenabol is very effective in losing weight, because it allows you to accelerate the burning of fat, faster to get the result and, equally important, get additional motivation to go forward to the goals.
S9009will give a head start and professional athletes, before which the goal is to dry before the competition and reduce the percentage of fat to a record 5-7%. S9009 is effective both in the course of solo and in combination with other products from us: Peptides, GR, sarms. The great effect is given by combinations of S9009 + Ibutamoren, S9009 + andarine (excellent combination!), S9009 + GHRP-2 or GHRP-6.
Is it wise to use sr9009 in the course of mass and strength? Definitely, yes. Increasing endurance will allow you to train more intensively and more efficiently, and this is tantamount to generating new growth stimuli. Acceleration of metabolism will help to recover faster, to develop muscles more often and with more load. With this mode of training does not have to wait long for muscle hypertrophy and growth of strength indicators!
The complex effect of sr9009 on metabolism makes it effective in the treatment of many metabolic disorders. Doctors successfully use the drug for the treatment of diabetes mellitus type 2. Assign patients with obesity and metabolic syndrome. S9009 is even used in sarcopenia-age atrophy of skeletal musculature (according to CDC is one of the five main risk factors of mortality of people over 65 years).
S9009l does not apply to hormones or hormone substances. It does not inhibit the synthesis of its own testosterone, is not subjected to aromatization with the formation of estrogen, is not toxic to the liver. SR9009 does not have a negative effect on organs and tissues susceptible to testosterone and dihydrotestosterone (prostate iron, hair bulbs), and therefore does not lead to side effects characteristic of AAs.
Recommended Dose: 2-3 capsules per day. The drug has a short half-life; The optimal mode of reception-1 capsule with an interval of 4-5 hours. The course lasts from 8 to 12 weeks.
YK11 - An innovative drug from the group Sarms, which helps to unlock the genetic code and open New horizons of muscle growth, burn and improve the composition of the body. The principle of yk11 is based on blocking the myostatin-inhibitor of muscle growth in the human body. On the course YK11 solo Wild Indices of anabolic processes, but there are no side effects peculiar to AAs.
The old-timers of the iron world know exactly about the regulatory protein, which is called myostatin. Those who hear about this peptide for the first time should get to know him. Myostatin performs a very specific function not only in the human body, but also in the body of many mammals. He's blocking muscle growth. You do not heard, myostatin blocks the growth of muscle fibers.
The only function of myostatin is to slow down the growth of muscle mass, so that the animal or man does not become a pile of unnecessary musculature, which is impossible to feed, and which does not fanatics ligaments and joints. Experiments on animals showed that the shutdown of myostatin receptors leads to an increase of dry mass by 200-300%. Known people who had mutation gene, coding myostatin. All of them differed abnormal (strong) development of muscle mass.
What relationship has to myostatine selective regulator of androgenic receptors yk11? The most direct. The mechanism of action of this sarms is realized through receptors to androgens, and the end result of interaction of yk11 with these receptors becomes production Follistatine - another signal protein which task is to deactivate Myostatin.
It turns out that yk11 stimulates the synthesis of "inhibitor inhibitor" of muscular growth. That is, increases the level of the regulator in the muscles, which inhibits the activity of another regulator, blocking muscle growth. The result of double negation is obvious-it is a rapid set of muscle mass!
YK11 is the newest drug in the World of sports pharmacy, but the results of the first experiments are impressive. When comparing the effect of identical doses of testosterone and yk11 in laboratory conditions, it was found that the intensification of anabolic processes in the muscle cells is higher if used yk11. In other words, it is at least not inferior in anabolic activity to testosterone, and thus is deprived of the side effects of AAS.
Even a solo course yk11 leads to forced muscular growth, this is eloquently evidenced by the increase in anabolic markers in muscle tissue. Experiments have shown that blocking of receptors of myostatin leads to a sharp set of dry weight at zero increase of fat. Moreover, myostatin blockers have lipolytic effect, which is manifested by accelerated fat and drawing of relief.
The relatively small experience of using YK11 in sports is explained by the fact that there are very few (almost no) genuine drugs on the market. Mainly under the guise of yk11 sold fakes, that is "dummy". YK11 is one of the few original YK11 preparations produced on GMP certified equipment in the USA.
For athletes and sports enthusiasts, YK11 opens the way to a rapid muscle mass. To mass building, which surpasses the effect of any other sarms! The second effect-catabolic, very useful in forming cycles on relief. Do not forget and lipolytic effect: without forced fat burning it is impossible to show a muscular pattern and go to the peak of competitive form!
The set of muscle mass is inseparable from the growth of power indicators. Powerlifters, weightlifters and strongman, as well as all fans of power training, NACELIVSHIESJA to a new personal record in bench or the mill, can take YK11 to increase the strength.
Mass
Weight
Drying
Formation of relief, preparation for competitions;
A course aimed at the growth of power indicators.
Warning! YK11 is not suitable for the prevention of sports injuries. Because of blocking myostatin begins the rapid growth of skeletal musculature, which is ahead of the strengthening of the joint-ligamentous apparatus. This can increase the risk of injury. For the prevention of injuries it is expedient to combine YK11 with andarine, growth hormone or peptides (TB-500, CJC-1295), contributing to the strengthening of tendons, ligaments and connective tissue as a whole.
Quick set of muscle mass;
No water retention;
Stable result without "rollback" after the course;
Increase of strength, endurance and peak strength;
No increase in estrogen levels, no risk of gynecomastia;
does not inhibit the synthesis of endogenous testosterone;
There are no side effects characteristic of testosterone, dihydrotestosterone and their synthetic derivatives.
Recommended Dose: 2 capsules per day, divided into two doses of 1 capsule. The duration of the course is from 4 to 8 weeks. In weight loss and in the course on relief it is expedient to combine Myostan with Andarine, and also to take L-carnitine, yohimbine hydrochloride, Sinefrin and Jekdizon. YK11 can be combined with Ligandrol or RAD-140.
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