Melanotan 2 Melanotan - peptide, synthetic analogue of natural peptide, which stimulates the synthesis of melanin and defines tanning skin), has the properties of aphrodisiac, which is confirmed by research. Until now there is no drug approved for use in humans, only laboratory substances are used for clinical trials, desp...
Melanotan 2 Melanotan - peptide, synthetic analogue of natural peptide, which stimulates the synthesis of melanin and defines tanning skin), has the properties of aphrodisiac, which is confirmed by research. Until now there is no drug approved for use in humans, only laboratory substances are used for clinical trials, despite this Melanotan 2 is actively distributed over the network, which creates a high risk Counterfeit products.
Melanotan 2 was first synthesized at the University of Arizona as a means to protect against skin cancer (since pigment melanin performs a protective function without missing ultraviolet rays). Scientists found that natural melanokortin has a short half-life, so it can not be used as a drug, so it was decided to modify its formula to improve the stability of the molecule. After the synthesis and screening of a large number of substances conducted by Victor J. Hruby and Mac E. Hadley, the peptide [Nle4, D-phe7]-α-MSH, which was about 1000 times more powerful than the natural melanokortin, was found. It was later named Melanotan 2 and was patented.
Melanotan 1 is a completely similar peptide, has undergone 3 phases of clinical trials, approved for use in humans under the brand Scenesse. Melanotan 1 By its properties acts more aimed at tanning, bypassing the impact on the libido function and is not a remedy. By its efficiency Melanotan 1 is inferior to Melanotan 2, but it is more safe for the body.
The first phase of the clinical trials was conducted by three men at the College of Medicine, Pharmacology Department, University of Arizona in Tucson, the results published in 1996. It was reported: "Melanotan 2 causes sunburn in humans after 5 small dosages subcutaneous injections." Among the side effects reported: mild nausea, yawning, spontaneous erection. A study on 10 men suffering erectile dysfunction was conducted later (1998). Scientists have concluded that Melanotan 2 in the dosage of 0.025 mg/kg eliminates dysfunction, even if it is psychogenic in nature. Another study of the year 2000 came to the same conclusion.
causes sunburn;
Increases libido and strengthens the erection (already 2 hours after the first injection);
Suppresses appetite.
The single dosage of Melanotan 2 is 250-500 mcg (exact calculation per kilogram of mass is not obligatory, as dosages vary widely) daily until the desired tan (15-20 days). The results are gradually over 1-3 weeks. To accelerate pigmentation, you can visit the solarium or sunbathe in the sun. Peptide injected subcutaneous insulin syringe, dissolved in water for injection.
The peptide is not approved by the FDA for use on humans. The known following side effects of Melanotan 2:
redness of the skin;
Nausea
Dark spots on the skin, which can increase in size (is reversible);
Theoretically, the defeat of the immune system and complications on the cardiovascular system. However, studies have revealed that melanocytes stimulation does not lead to damages.
The third phase of clinical trials Melanotan 1 has been completed, approved for application by the European Medicines Agency (EMA) Name Review Group (NRG), which is a significant confirmation of security.
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