What is CJC-1295 no DAC ?

CJC-1295 no DAC - a peptide hormone, which consists of 30 amino acids. In the human body functions as an analogue somatoliberin (natural stimulant secretion growth hormone).

One of the main advantages of CJC-1295 DAC compared to the widely used analogue GRF (1-29) (Synonyms: CJC-1295 w/O, without or without DAC) is a long period of Polurazrushenija (up to two weeks). CJC-1295 DAC is associated with plasma proteins (albumins), which leads to a significant increase in the duration of the action, by adding lysine associated with non-peptide molecule DAC (Drug Affinity Complex).

Be sure to specify when buying, whether there is a molecule CJC-1295 DAC (Drug Affinity Complex), this will depend on the effectiveness and scheme of the course. If there is no Drug Affinity Complex in the structure, then you acquire Tetrazameshhennyj or modified GRF (1-29), which sellers often call SJS-1295, this peptide is valid for approximately 30 minutes.

Storage conditions: 2-8 C degrees (refrigerator).

Method of application: injection subcutaneous or intramuscularly.

CJC-1295 no DAC

The CJC-1295 DAC was invented by the Canadian biotechnology company Conjuchem in 2005, but the popularity in bodybuilding gained only by 2010-2011 year, when the technology of production took possession of third-party companies, including Chinese manufacturers. The duration (half-life period) is 6-8 days.

The Conjuchem company initiated research on the CJC-1295 DAC in 2005, which was aimed at examining the effects of the substance on visceral fat in patients suffering from AIDS and obesity. It is known that earlier in such situations the growth hormone for fat burning was used. The results were very successful for most patients, but studies were suspended after the lawsuits were filed by three patients who suffered myocardial infarction after the CJC-1295 DAC course.

Effect of Modified GRF

CJC-1295 acts on the nucleus of the anterior lobe of the pituitary gland and stimulates the secretion of growth hormone, mainly by means of Camp Zavismogo path. The substance binds to the receptors GHRH, which are related to the group G-protein conjugate receptors.

Effects of CJC-1295 no DAC (Mod-GRF)

Studies have shown that the CJC-1295 DAC has similar effects to the growth hormone:

   Increased strength;

   Muscle growth;

   Fat burning;

   Improvement of skin quality (wrinkle smoothing);

   Increase in bone density;

   Reinforcement of ligaments and joints;

   Positive effect on sleep;

   A brief overview of the physiology of growth hormone.

The release of growth hormone by the pituitary gland depends on the three main types of hormone regulators:

Somatostatin, which inhibits the secretion of growth hormone, it provides a curve secretion (creates peaks concentration in certain hours, particularly at night).

The growth hormone releasing hormone (GHRH) is a stimulating release of the peptide. The introduction to the body causes a undulating rise in concentration, which will be weak in the hours when the natural secretion of the growth hormone is reduced by somatostatin, and high during the natural recovery of the concentration of the growth hormone (eg, at night). In other words, GHRH enhances the secretion of the growth hormone without disturbing the natural pulsoobraznuju curve. Artificial analogues: GRF (1-29), it is Sermorelin and CJC-1295.

Ghrelin (GHRP)-is a modulator of secretion, that is, regulates the balance between peaks and drops of concentration of growth hormone. Artificial analogues are GHRP-6, GHRP-2, Hexarelin and Ipamorelin. Create a peak concentration of growth hormone immediately after the introduction, regardless of the time of day and the presence of somatostatin in the blood. With age ghrelin allows to keep secretion of growth hormone, despite the ever increasing influence of somatostatin.

Basic combined Course CJC-1295 no DAC + GHRP-6

It has been well proven and precisely established that the simultaneous introduction of GHRH (e.g. CJC-1295) and GHRP (e.g. GHRP-6 or GHRP-2) leads to synergies effect. These peptides have potencirujushhim effect on each other. In other words, with the introduction of one CJC-1295 we will get a stimulating effect of 2 points. With the introduction of one only GHRP-6 will get an effect of 4 points. When you enter both substances at the same time, we will have an effect of not 6 points (Additive action 2 + 4 = 6), as you might expect, and in 10 points-more than the sum of each separately (potentiating action 2 + 4 = 10). Thus, we get not only a greater anabolic response, but also can save money.

Despite the fact that the natural pulsation of growth hormone in the introduction of CJC-1295 persists, it does not cause an increase in these peaks, raising only the basal level of growth hormone, thus creating a pattern of concentration on the female type with a smaller Anabolic response. Moreover, GHRH are effective only when the level of somatostatin is low. Therefore the combination of CJC-1295 and GHRP-6 or GHRP-2 allows to preserve a natural curve, and to regulate time and height of peaks of concentration.

Optimal combined Course with Modified GRF (1-29):

GHRP-6 or GHRP-2 to 100 mcg three times a day.

CJC-1295 to 1000 MCG twice a week.

Course duration 8-12 weeks.

The efficiency is equated to a cycle of growth hormone of 15 ed/day, with the cost several times lower.

Course CJC-1295 without DAC

Optimal dosage of CJC-1295 without DAC: 1 μ g/kg up to three times a day (with subcutaneous injection) (in the ampoule 2mg = 2000mkg). Thus, at weight 90 kg the relevant dosage will be 90mkg, and one vial is enough for 8-22 days (depending on frequency of reception)

This peptide is also desirable to combine with GHRP-6 or GHRP-2. For example, the standard protocol looks like this: One injection contains 100 mcg GHRP-6 + 100 mcg of Modified GRF (1-29). Dissolve can be in one syringe. The solution is found 2-3 times a day, with a difference of at least 3 hours. The best time to inject: after training, 15 minutes before the meal and before bedtime!

Dosage and Reception mode of CJC-1295 no DAC:

   100 mcg CJC-1295 together with 200 MCG GHRP-6 in the morning 25 minutes before the meal;

   100 mcg CJC-1295 together with 200 MCG GHRP-6 after 6 hours, ideally immediately after training;

   100 mcg CJC-1295 together with 200 mcg GHRP-6 just before going to sleep.

Main effects of CJC-1295 no DAC

   increase of power indicators;

   Muscle growth;

   Fat burning.

   Secondary effects:

   Strengthening ligaments, joints, bones;

   strengthening of immunity;

   Rejuvenating effect;

   Improvement of skin and hair properties;

   increase of relief;

   Protects the liver;

   Anti-inflammatory effect.

Side effects of CJC-1295 no DAC

In the course of studies serious side effects were not recorded, in contrast, the drug increased the protective properties of the body. GHRP-6 appointed even in childhood.

Storage condition of CJC-1295 no DAC:

   In powder at + 2-8 from-to 2let;

   In powder at room themes-re-up to 30 days;

   In the solution at + 2-8 C-up to 20 days;

   In the solution at room theme-re-up to 3 hours.

Store necessary in a dark place, freezing is not desirable