1. What is HCG 5000 I.E. and what is it used for?

The active ingredient of HCG 5000 I.E. belongs to the group of gonadotropins (sex hormones) that regulate the release of egg cells from the ovary in women and in men the production of the male hormone testosterone.

HCG 5000 I.E. contains as active ingredient chorionic gonadotropin (hCG) - a protein hormone, which is obtained from the urine of pregnant women. Gonadotropins play an important role in fertility and reproduction.

women

    HCG 5000 I.E. is used in female infertility to induce ovulation (ovulation triggering).
    HCG 5000 I.E. is also used in conjunction with other fertility medicines to support the production of oocytes in the context of assisted reproduction (IVF).

Men

    HCG 5000 I.E. is used in men to assess the functioning of the testes in the case of sub-function of the sex organs due to a lack of sex hormones before a stimulation therapy.

children

    HCG 5000 I.E. is used in boys with late onset puberty (pubertas tarda).

2. What should you do before using HCG 5000 I.E. note?

HCG 5000 I.E. may not be used

    If you are allergic to chorionic gonadotropin or any of the other ingredients of this medicine (listed in section 6)
    in tumors of the hypothalamus (part of the diencephalon) or the pituitary (pituitary gland)
    if you have enlargement of the ovaries or one or more ovarian cysts that are not based on polycystic ovarian syndrome
    if you have bleeding of unexplained cause from the vagina
    if you have had ovarian, uterine or breast cancer
    if you had an ectopic pregnancy within the last three months
    if you have severe phlebitis or blood clots in the veins (active thromboembolic disease)
    if you have ovarian hyperstimulation syndrome (OHSS - ovarian hyperstimulation syndrome)
    if normal pregnancy is not possible for organic reasons, e.g. malfunction of the ovaries, malformations of the reproductive organs that are not compatible with pregnancy, or in connective tissue tumors, or if you have already reached the menopause
    if you have sex hormone-dependent tumors, such as Prostate cancer or breast cancer (in men) known or suspected,

Warnings and Precautions

Please talk to your doctor or pharmacist before using HCG 5000 I.E. apply.

Tell your doctor if you have or have had any of the following conditions because of the use of HCG 5000 I.E. can lead to a deterioration:

    Cardiovascular disease
    kidney disease
    Epilepsy (epilepsy)
    Migraine-like headache

Treatment with HCG 5000 I.E. can increase the risk of thrombosis. A thrombosis is the formation of a blood clot in a blood vessel, usually in the veins of the legs or lungs. Even the pregnancy itself can be an increased risk for the occurrence of thrombosis. Please contact your doctor before using HCG 5000 I.E. start when

    You already know that you have an increased risk of thrombosis
    You or someone from your close relationship already had a thrombosis
    You are severely overweight

Before your doctor begins treatment, the causes of your infertility or that of your partner, and possible contraindications for pregnancy, must be clear. Your doctor must conduct a thorough examination to rule out changes in the genitals or non-gonadal hormonal imbalances (such as thyroid, adrenals or pituitary gland disorders).

During treatment, close monitoring by your doctor is very important. Usually, ultrasound examinations are performed at regular intervals and blood is collected. This is especially important as you are treated by treatment with HCG 5000 I.E. are at increased risk of developing Ovarian Hyperstimulation Syndrome (OHSS) (see also section 4 "Possible side effects"). This happens when the ovaries overreact to treatment and produce too many follicles. As a rule, an OHSS returns automatically during the menstrual period. OHSS can be more severe and protracted after pregnancy. Therefore, medical checks are recommended for at least two weeks after hCG application.

Symptoms of mild and moderate OHSS are:

    Abdominal pain or discomfort
    bloated stomach
    nausea
    Vomit
    diarrhea
    increase in weight

In severe cases of OHSS, additional symptoms may occur such as:

    difficult breathing
    reduced urination

Very rarely, complications such as ovarian rotation and blood clots in veins or arteries can occur in severe cases of OHSS.

Talk to your doctor immediately, even if the symptoms do not appear until a few days after the last injection. These may be signs of increased ovarian activity that could become severe. If these symptoms become severe, treatment for infertility must be stopped and you need to be treated in the hospital.

Adherence to the recommended dosage and careful monitoring of your treatment reduce the risk of these symptoms.
Patients with ovarian dysfunction with increased follicle formation (polycystic ovarian syndrome) are at increased risk for OHSS.

If gonadotropin therapy leads to pregnancy, the likelihood of having twins or multiple births is increased.

The number of miscarriages both in patients who do not or not enough oocytes, as well as in women who undergo a technique of assisted reproduction, such as. IVF, is higher than the average population, but comparable to the miscarriage rates in women with other fertility disorders.

In women with premature fallopian tubes, there is a slightly increased risk of ectopic pregnancy.

The incidence of malformations following assisted reproductive technology may be slightly higher than with natural conception. This may be related to different preconditions in the parents (for example, age of the mother, sperm quality) and the increased incidence of multiple pregnancies.

Your doctor will especially monitor you during treatment if you have a clinically significant illness that could lead to a worsening of your condition.

After the application of HCG 5000 I.E. It can lead to a false positive pregnancy test for up to 10 days.

children
To avoid bone problems or premature puberty, HCG 5000 I.E. be used with caution in boys before puberty. Skeletal development should be monitored regularly.
Effects of misuse for doping purposes

The application of HCG 5000 I.E. can lead to positive results in doping controls.
The application of HCG 5000 I.E. as a doping agent can lead to a risk to health.
Application of HCG 5000 I.E. with other medicines

Tell your doctor or pharmacist if you are taking, have recently taken or might take or intend to take any other medicines.

Interactions with other medicinal products are unknown.
Pregnancy, breastfeeding and fertility

HCG 5000 I.E. is used to treat infertility (see section 1 "What is HCG 5000 I.E. and what is it used for?").

HCG 5000 I.E. should not be used during pregnancy and breast-feeding.

3. What is HCG 5000 I.E. apply?

Always use this medicine exactly as your doctor has told you. Ask your doctor if you are not sure.
Type of application:

This medicine is given to you by a doctor experienced in the treatment of fertility problems in a muscle.

To induce ovulation and stimulation of the ovaries:
The recommended dose is once 5000 I.E. or 10,000 I.E. hCG (equivalent to 1 or 2 vials HCG 5000 I.E.). The application should take place 24 to 48 hours after reaching the optimal stimulation of the ovaries.
When HCG 5000 I.E. It is recommended to have sexual intercourse on the day of injection and the following day to induce ovulation after stimulation of the ovaries.

Verification of the functioning of the testes in case of subfunction of the sexual organs due to a lack of sex hormones:
The recommended dose is once 5000 I.E. hCG (equivalent to 1 vial of HCG 5000 I.E.).

children
In boys with late puberty:
The recommended dose is: 5000 I.U. hCG (equivalent to 1 vial of HCG 5000 I.U.) weekly for 3 months.

In boys who have no testicles, or in boys with only one testicle (differential diagnosis of undescended testes):
The recommended dose is once 5000 I.E. hCG (equivalent to 1 vial of HCG 5000 I.E.).
If you use a larger quantity HCG 5000 I.E. have applied as you should

No cases of acute overdose have been reported. However, there is a possibility that in women overdose may trigger ovarian hyperstimulation syndrome (see section 2 "What you should know before you use HCG 5000 I.E.").
When using the HCG 5000 I.E. have forgotten

Do not apply twice the amount if you have forgotten the previous application. Talk to your doctor.
When using the HCG 5000 I.E. abort, stop

Talk to your doctor.

4. What side effects are possible frpm HCG 5.000 i.E.?

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Hormones for the treatment of infertility, e.g. The hCG in HCG 5000 I.E., may cause increased activity in the ovaries and lead to ovarian hyperstimulation syndrome (OHSS). Symptoms may include abdominal pain, bloated stomach, nausea, vomiting, diarrhea, and weight gain. In severe cases of OHSS, fluid accumulation in the abdomen, pelvis and / or chest cavity, labored breathing, and decreased urination may occur. Rare complications such as blood clots in blood vessels (thromboembolism) and ovarian rotation (ovarian torsion) have been reported in severe cases of OHSS. If you notice any of these symptoms, contact your doctor immediately, even if the symptoms do not appear until a few days after the last injection.

Allergic reactions (hypersensitivity reactions) may occur in connection with the application of HCG 5000 I.E. occur. Symptoms may include rash, itching, swelling of the throat and labored breathing. If you notice these symptoms, contact your doctor immediately.

Very common: may affect more than 1 in 10 people

    Enlargement of male mammary glands (gynecomastia)
    a headache
    Reactions and pain at the injection site

Common: may affect up to 1 in 10 people

    Nausea, abdominal pain, vomiting
    mild to moderate overstimulation syndrome of the ovaries (OHSS), swelling of the chest, testicular pain
    Hot flashes (only observed in men)
    Rash, seborrhea (acne vulgaris)

Uncommon: may affect up to 1 in 100 people

    diarrhea
    Disruption of salts and water
    severe overstimulation syndrome of the ovaries (OHSS)
    Depression, irritability, restlessness

Not known (frequency can not be estimated from the available data):

    Hypersensitivity reactions (allergic reactions)
    Formation of blood clots in blood vessels
    bloated stomach
    Rash, itchy hives (hives), itching
    Sensitivity and pain in the chest
    Fever, fatigue (fatigue), weakness (asthenia)

Increases in size of the male limb with tendency to stiffening or enlargement of the prostate gland were observed.

Additional side effects in children and adolescents
Occasionally, mild psychological changes may occur in boys during treatment, as observed at the beginning of puberty (adolescent behavior).

5. How is HCG 5000 I.E. Storing?

Keep this medicine out of the sight and reach of children.

You must stop using the medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of the specified month.